Representative Publications
Visual Perception and Sensory Readout
Cone JJ, Mitchell AO, Parker RK, Maunsell JHR. Stimulus dependent differences in cortical versus subcortical contributions to visual detection in mice. Current Biology (2024). PMID: 38640924
Day-Cooney JR, Cone JJ, Maunsell JHR. Perceptual weighting of V1 spikes revealed with white noise optogenetic stimulation. Journal of Neuroscience (2022). PMID: 35232760
Cone JJ, Bade ML, Masse NY, Page, EA, Maunsell JHR. Mice preferentially use increases in cerebral cortex spiking to detect changes in visual stimuli. Journal of Neuroscience (2020). PMID: 32917791
Cone JJ, Scantlen MD, Histed MH, Maunsell JHR. Different inhibitory interneuron cell classes make distinct contributions to visual perception. eNeuro (2019). PMID: 30868104
Cone JJ, Ni AM, Ghose K, Maunsell JHR. Electrical Microstimulation of Visual Cerebral Cortex Elevates Psychophysical Detection Thresholds. eNeuro (2018). PMID: 30406199
Dopamine Signaling and Reinforcement Learning
Duriez A, Bergerot C, Cone JJ, Roitman MF, Gutkin B. Homeostatic Reinforcement Theory Accounts for Sodium Appetitive State- and Taste-Dependent Dopamine Responding. Nutrients (2023). PMID: 36839372
Cone JJ, Fortin SM, McHenry JA, Stuber GD, McCutcheon JE, Roitman MR. Physiological state gates acquisition and expression of mesolimbic reward prediction errors. Proceedings of the National Academy of Sciences (2016). PMID: 26831116
Cone JJ, Roitman JD, Roitman MF. Ghrelin regulates phasic mesolimbic signaling evoked by food-predictive stimuli. Journal of Neurochemistry (2015). PMID: 25708523
Cone JJ, McCutcheon JE, Roitman MF. Ghrelin acts as an interface between physiological state and phasic dopamine signaling. Journal of Neuroscience (2014). PMID: 24695709
Cone JJ, Chartoff EH, Potter DN, Ebner SR, Roitman MF. Prolonged high-fat diet reduces dopamine reuptake without altering DAT gene expression. PLoS One (2013). PMID: 23516454
Brown HD, McCutcheon JE, Cone JJ, Ragozzino ME, Roitman MF. Primary food reward and reward predictive stimuli evoke different patterns of phasic dopamine signaling throughout the striatum. European Journal of Neuroscience (2011). PMID: 22122410
Dopamine Signaling and Locomotor Control
Ryczko D, Grätsch S, Alpert MH, Cone JJ, Kasemir J, Ruthe A, Beauséjour P-A, Auclair F, Alford S, Roitman MF, Dubuc R. Descending dopaminergic inputs to reticulospinal neurons promote locomotor movements. Journal of Neuroscience (2020). PMID: 32998974
Ryczko D, Cone JJ, Alpert MH, Goetz L, Auclair F, Dubé C, Parent M, Roitman MF, Alford S, Dubuc R. Descending dopamine pathway conserved from vertebrates to mammals. Proceedings of the National Academy of Sciences (2016). PMID: 27071118
Ryczko D, Grätsch S, Auclair F, Dubé C, Bergeron S, Alpert MH, Cone JJ, Roitman M, Alford S, Dubuc R. Forebrain dopamine neurons project down to a brainstem region controlling locomotion. Proceedings of the National Academy of Sciences (2013). PMID: 23918379